References to Fat Profile of Meat Blog:
https://arizonanaturopath.com/fat-profile-of-meat-surprise-worst-meat/
The sugar industry paid for research that singled out fat and cholesterol as the dietary causes of CHD and downplayed evidence that sucrose consumption was also a risk factor. Kearns CE, Schmidt LA, Glantz SA. Sugar Industry and Coronary Heart Disease Research: A Historical Analysis of Internal Industry Documents. JAMA Intern Med. 2016 Nov 1;176(11):1680-1685. doi: 10.1001/jamainternmed.2016.5394. Erratum in: JAMA Intern Med. 2016 Nov 1;176(11):1729. doi: 10.1001/jamainternmed.2016.6774. PMID: 27617709; PMCID: PMC5099084.
According to French et al. [29] the most undesirable fatty acid is myristic acid, which only represents 1.3% in chicken fat by-products (Table 3), 3% in beef tallow and 3.5% in pork backfat (Table 5). Several authors have reported that palmitic acid has a low hypercholesterolemic effect and stearic acid has no effect because it becomes oleic acid in the body [30] and so does not influence blood cholesterol levels. https://pmc.ncbi.nlm.nih.gov/articles/PMC7466361/ French M.A., Sundram K., Clandinin M.T. Cholesterolaemic effect of palmitic acid in relation to other dietary fatty acids. Asia Pac. J. Clin. Nutr. 2002;11:401–407. doi: 10.1046/j.1440-6047.11.s.7.3.x.
However, according to Freigang 2023, Oleic acid selectively elicits IL-1a secretion from macrophages. IL-1a is a powerful trigger of inflammation and promoter of chronic inflammatory processes. IL-1a producing fatty acids like oleic acid, arachidonic acid found abundantly in arteriosclerotic plaque can potentially increase the size of plaque. https://pubmed.ncbi.nlm.nih.gov/23995233/ Freigang S, Ampenberger F, Weiss A, Kanneganti TD, Iwakura Y, Hersberger M, Kopf M. Fatty acid-induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis. Nat Immunol. 2013 Oct;14(10):1045-53. doi: 10.1038/ni.2704. Epub 2013 Sep 1. PMID: 23995233.